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Fully integrated approach: an alternative solution of coupling a GIS and diffuse pollution models

S. LIU,R.E. BRAZIER,A. L. HEATHWAITE,W. LIU

Frontiers of Environmental Science & Engineering 2014, Volume 8, Issue 4,   Pages 616-623 doi: 10.1007/s11783-013-0589-x

Abstract: pollution and visualize the results in a spatial context.A common question in integrating diffuse pollution models and GIS is to choose a suitable coupling approach, in which the feature of diffuse pollution models should be taken into account.In this paper, we report on our experience in coupling a distributed diffuse pollution model with a GISpollution modes.

Keywords： diffuse pollution     GIS     modeling     nutrients     phosphorus    

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Suitability of common models to estimate hydrology and diffuse water pollution in North-eastern German

Muhammad WASEEM, Frauke KACHHOLZ, Jens TRÄNCKNER

Frontiers of Agricultural Science and Engineering 2018, Volume 5, Issue 4,   Pages 420-431 doi: 10.15302/J-FASE-2018243

Abstract:

Various process-based models are extensively being used to analyze and forecast catchment hydrology and water quality. However, it is always important to select the appropriate hydrological and water quality modeling tools to predict and analyze the watershed and also consider their strengths and weaknesses. Different factors such as data availability, hydrological, hydraulic, and water quality processes and their desired level of complexity are crucial for selecting a plausible modeling tool. This review is focused on suitable model selection with a focus on desired hydrological, hydraulic and water quality processes (nitrogen fate and transport in surface, subsurface and groundwater bodies) by keeping in view the typical lowland catchments with intensive agricultural land use, higher groundwater tables, and decreased retention times due to the provision of artificial drainage. In this study, four different physically based, partially and fully distributed integrated water modeling tools, SWAT (soil and water assessment tool), SWIM (soil and water integrated model), HSPF (hydrological simulation program– FORTRAN) and a combination of tools from DHI (MIKE SHE coupled with MIKE 11 and ECO Lab), have been reviewed particularly for the Tollense River catchment located in North-eastern Germany. DHI combined tools and SWAT were more suitable for simulating the desired hydrological processes, but in the case of river hydraulics and water quality, the DHI family of tools has an edge due to their integrated coupling between MIKE SHE, MIKE 11 and ECO Lab. In case of SWAT, it needs to be coupled with another tool to model the hydraulics in the Tollense River as SWAT does not include backwater effects and provision of control structures. However, both SWAT and DHI tools are more data demanding in comparison to SWIM and HSPF. For studying nitrogen fate and transport in unsaturated, saturated, and river zone, HSPF was a better model to simulate the desired nitrogen transformation and transport processes. However, for nitrogen dynamics and transformations in shallow streams, ECO Lab had an edge due its flexibility for inclusion of user-desired water quality parameters and processes. In the case of SWIM, most of the input data and governing equations are similar to SWAT but it does not include water bodies (ponds and lakes), wetlands and drainage systems. In this review, only the processes that were needed to simulate the Tollense River catchment were considered, however the resulted model selection criteria can be generalized to other lowland catchments in Australia, North-western Europe and North America with similar complexity.

Keywords： diffuse pollution     ECO Lab     HSPF     lowland catchment     MIKE 11     MIKE SHE     modeling tools     SWAT     SWIM     Tollense River    

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Temporal and spatial stability of the EM/PM molecular subtypes in adult diffuse glioma

Frontiers of Medicine 2023, Volume 17, Issue 2,   Pages 240-262 doi: 10.1007/s11684-022-0936-z

Abstract: Detailed characterizations of genomic alterations have not identified subtype-specific vulnerabilities in adult gliomas. Mapping gliomas into developmental programs may uncover new vulnerabilities that are not strictly related to genomic alterations. After identifying conserved gene modules co-expressed with EGFR or PDGFRA (EM or PM), we recently proposed an EM/PM classification scheme for adult gliomas in a histological subtype- and grade-independent manner. By using cohorts of bulk samples, paired primary and recurrent samples, multi-region samples from the same glioma, single-cell RNA-seq samples, and clinical samples, we here demonstrate the temporal and spatial stability of the EM and PM subtypes. The EM and PM subtypes, which progress in a subtype-specific mode, are robustly maintained in paired longitudinal samples. Elevated activities of cell proliferation, genomic instability and microenvironment, rather than subtype switching, mark recurrent gliomas. Within individual gliomas, the EM/PM subtype was preserved across regions and single cells. Malignant cells in the EM and PM gliomas were correlated to neural stem cell and oligodendrocyte progenitor cell compartment, respectively. Thus, while genetic makeup may change during progression and/or within different tumor areas, adult gliomas evolve within a neurodevelopmental framework of the EM and PM molecular subtypes. The dysregulated developmental pathways embedded in these molecular subtypes may contain subtype-specific vulnerabilities.

Keywords： glioma progression     molecular classification     EM/PM subtyping     intratumor heterogeneity    

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Immunosuppressive tumor microenvironment contributes to tumor progression in diffuse large B-cell lymphoma

Frontiers of Medicine 2023, Volume 17, Issue 4,   Pages 699-713 doi: 10.1007/s11684-022-0972-8

Abstract: achieved 40%–50% long-term complete response in relapsed or refractory diffuse

Keywords： anti-CD19 chimeric antigen receptor T     immunotherapy     diffuse large B cell lymphoma     tumor microenvironment    

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Phase I study of CBM.CD19 chimeric antigen receptor T cell in the treatment of refractory diffuse large

Frontiers of Medicine 2022, Volume 16, Issue 2,   Pages 285-294 doi: 10.1007/s11684-021-0843-8

Abstract: second-generation anti-CD19 CAR bearing 4-1BB costimulatory molecule, for the treatment of patients with refractory diffuse

Keywords： CAR-T cell therapy     refractory diffuse large B-cell lymphoma     cytokine release syndrome     dose-limiting    

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Treatment of severe diffuse cavernous hemangioma of the lower limb by combination of superficial femoral

Yin XIA, Dan SHANG, Qin LI, Xiaoqin RUN, Chenxi OUYANG, Yiqing LI, Bi JIN

Frontiers of Medicine 2009, Volume 3, Issue 2,   Pages 240-244 doi: 10.1007/s11684-009-0031-8

Abstract: Severe diffuse cavernous hemangioma of the lower limb is rarely seen among young people and sometimesWe reported a case of diffuse cavernous hemangioma involving both skin and muscles of the left lower

Keywords： cavernous hemangioma     femoral artery     ligation     amputation    

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Presence of multiple abnormal immunologic markers is an independent prognostic factor of diffuse large

Yiwen Cao, Zhenhua Liu, Wen Wu, Ying Qian, Qin Shi, Rong Shen, Binshen Ouyang, Pengpeng Xu, Shu Cheng, Jin Ye, Yiming Lu, Chaofu Wang, Chengde Yang, Li Wang, Weili Zhao

Frontiers of Medicine 2019, Volume 13, Issue 1,   Pages 94-103 doi: 10.1007/s11684-019-0680-1

Abstract: to analyze the prognostic value of pretreatment immunologic markers in newly diagnosed patients with diffuse

Keywords： immunologic marker     diffuse large B-cell lymphoma     prognosis    

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Health impacts of air pollution in China

Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 4, doi: 10.1007/s11783-020-1367-1

Abstract:

•Impacts of air pollution on various body systems health in China were

Keywords： Health impacts     Air pollution     China     Advances    

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Environmental pollution and DNA methylation: carcinogenesis, clinical significance, and practical applications

Yi Cao

Frontiers of Medicine 2015, Volume 9, Issue 3,   Pages 261-274 doi: 10.1007/s11684-015-0406-y

Abstract:

Environmental pollution is one of the main causes of human cancer.Epigenetic changes caused by environmental pollution play important roles in the development and progressionof environmental pollution-related cancers.Furthermore, prospective applications of DNA methylation to environmental pollution detection and cancer

Keywords： environmental pollution     DNA methylation     cancer     biomarker     diagnosis     therapy     prevention    

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Investigating the impact of air pollution on AMI and COPD hospital admissions in the coastal city of

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 5, doi: 10.1007/s11783-021-1490-7

Abstract:

• The impact of air pollution on AMI/COPD hospital admissions were examined

Keywords： AMI     COPD     Air pollution exposure     GAM    

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Experimental study of pollution effect on the behavior of high voltage insulators under alternative current

Hani BENGUESMIA, Nassima M’ZIOU, Ahmed BOUBAKEUR

Frontiers in Energy 2021, Volume 15, Issue 1,   Pages 213-221 doi: 10.1007/s11708-017-0479-1

Abstract: In this paper, the impact of the conductivity and the distribution of pollution on the behavior of theFor this comparative study, different solutions are adopted to s`imulate the pollution (containing NaCl+ distilled water) that has different conductivities for a discontinuous distribution of the pollutionFurthermore, the influence of the pollution on the flashover voltage and the leakage current is studied

Keywords： 1512L insulator     circular model     artificial pollution     flashover     leakage current     discontinuous pollution    

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A critical review of the emerging research on the detection and assessment of microplastics pollution

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 10, doi: 10.1007/s11783-022-1563-2

Abstract:

● Coastal and marine regions are the most studied for microplastic pollution

Keywords： Plastic pollution     Waste management     Global south     Sustainability     Marine pollution    

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System engineering for water pollution control at the watershed level in China

Wei MENG,

Frontiers of Environmental Science & Engineering 2009, Volume 3, Issue 4,   Pages 443-452 doi: 10.1007/s11783-009-0037-0

Abstract: The present water pollution situation at watershed level in China has been systematically analyzed.The causes of water pollution are attributed to the extensive economic developmental pattern, poor wastewatertreatment, and a lack of nonpoint pollution control.From 2006 to 2020, water pollution control and governance will be a national key specific project ofThe strategies of this project include establishing a water pollution control system at watershed level

Keywords： water pollution control     watershed     system engineering     sustainability     integrated watershed management     key    

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ENHANCING RAINFALL-RUNOFF POLLUTION MODELING BY INCORPORATION OF NEGLECTED PHYSICAL PROCESSES

Frontiers of Agricultural Science and Engineering 2023, Volume 10, Issue 4,   Pages 553-565 doi: 10.15302/J-FASE-2023519

Abstract:

The growing need to mitigate rainfall-runoff pollution, especially first flush, calls for accuratequantification of pollution load and the refined understanding of its spatial-temporal variation.The wash-off model has advantages in modeling rainfall-runoff pollution due to the inclusion of two keycharacteristics dominated by land pollution and rainfall pollution, respectively.The enhanced model can provide deeper insights into non-point pollution mitigation.

Keywords： Erhai Lake     field experiment     non-point source     pollution load     rainfall runoff     wash-off model    

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IMPROVING NITROGEN SAFETY IN CHINA: NITROGEN FLOWS, POLLUTION AND CONTROL

Frontiers of Agricultural Science and Engineering 2022, Volume 9, Issue 3,   Pages 465-474 doi: 10.15302/J-FASE-2022454

Abstract:

● It is necessary to address the N flows and their impacts on environment in China for sustainable N management.

Keywords： barriers     future management     ammonia emissions     nitrogen input     water N pollution    

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Title Author Date Type Operation

Fully integrated approach: an alternative solution of coupling a GIS and diffuse pollution models

S. LIU,R.E. BRAZIER,A. L. HEATHWAITE,W. LIU

Journal Article

Suitability of common models to estimate hydrology and diffuse water pollution in North-eastern German

Muhammad WASEEM, Frauke KACHHOLZ, Jens TRÄNCKNER

Journal Article

Temporal and spatial stability of the EM/PM molecular subtypes in adult diffuse glioma

Journal Article

Immunosuppressive tumor microenvironment contributes to tumor progression in diffuse large B-cell lymphoma

Journal Article

Phase I study of CBM.CD19 chimeric antigen receptor T cell in the treatment of refractory diffuse large

Journal Article

Treatment of severe diffuse cavernous hemangioma of the lower limb by combination of superficial femoral

Yin XIA, Dan SHANG, Qin LI, Xiaoqin RUN, Chenxi OUYANG, Yiqing LI, Bi JIN

Journal Article

Presence of multiple abnormal immunologic markers is an independent prognostic factor of diffuse large

Yiwen Cao, Zhenhua Liu, Wen Wu, Ying Qian, Qin Shi, Rong Shen, Binshen Ouyang, Pengpeng Xu, Shu Cheng, Jin Ye, Yiming Lu, Chaofu Wang, Chengde Yang, Li Wang, Weili Zhao

Journal Article

Health impacts of air pollution in China

Journal Article

Environmental pollution and DNA methylation: carcinogenesis, clinical significance, and practical applications

Yi Cao

Journal Article

Investigating the impact of air pollution on AMI and COPD hospital admissions in the coastal city of

Journal Article

Experimental study of pollution effect on the behavior of high voltage insulators under alternative current

Hani BENGUESMIA, Nassima M’ZIOU, Ahmed BOUBAKEUR

Journal Article

A critical review of the emerging research on the detection and assessment of microplastics pollution

Journal Article

System engineering for water pollution control at the watershed level in China

Wei MENG,

Journal Article

ENHANCING RAINFALL-RUNOFF POLLUTION MODELING BY INCORPORATION OF NEGLECTED PHYSICAL PROCESSES

Journal Article

IMPROVING NITROGEN SAFETY IN CHINA: NITROGEN FLOWS, POLLUTION AND CONTROL

Journal Article